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High-speed atomic force microscopy directly visualizes conformational dynamics of the HIV Vif protein in complex with three host proteins

Vif (viral infectivity factor) is a protein that is essential for the replication of the HIV-1 virus. The key function of Vif is to disrupt the antiviral activity of host APOBEC3 (apolipoprotein B mRNA-editing enzyme catalytic subunit 3) proteins, which mutate viral nucleic acids. Inside the cell, V...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pan, Yangang, Shlyakhtenko, Luda S., Lyubchenko, Yuri L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443491/
https://ncbi.nlm.nih.gov/pubmed/32587092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014442
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