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Visualization of supercoiled DNA with atomic force microscopy in situ

Tertiary structure of supercoiled DNA is a significant factor in a number of genetic functions and is apparently affected by environmental conditions. We applied atomic force microscopy (AFM) for imaging the supercoiled DNA deposited at different ionic conditions. We have employed a technique for th...

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Main Authors: Lyubchenko, Yuri L., Shlyakhtenko, Luda S.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC19541/
https://ncbi.nlm.nih.gov/pubmed/9012812
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