Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) has a dismal prognosis, and survival benefits of recent multimodality treatments remain small. Cancer-associated fibroblasts (CAFs) are known to contribute to poor outcome by conferring therapy resistance to various cancer types, but this has not been explored in EAC....

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ebbing, Eva A., van der Zalm, Amber P., Steins, Anne, Creemers, Aafke, Hermsen, Simone, Rentenaar, Rosa, Klein, Michelle, Waasdorp, Cynthia, Hooijer, Gerrit K. J., Meijer, Sybren L., Krishnadath, Kausilia K., Punt, Cornelis J. A., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., van Delden, Otto M., Hulshof, Maarten C. C. M., Medema, Jan Paul, van Laarhoven, Hanneke W. M., Bijlsma, Maarten F.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369811/
https://ncbi.nlm.nih.gov/pubmed/30670657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820459116
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares