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Thermodynamic phase diagram of amyloid-β (16–22) peptide

The aggregation of monomeric amyloid β protein (Aβ) peptide into oligomers and amyloid fibrils in the mammalian brain is associated with Alzheimer’s disease. Insight into the thermodynamic stability of the Aβ peptide in different polymeric states is fundamental to defining and predicting the aggrega...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wang, Yiming, Bunce, Samuel J., Radford, Sheena E., Wilson, Andrew J., Auer, Stefan, Hall, Carol K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369758/
https://ncbi.nlm.nih.gov/pubmed/30674664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819592116
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