Thermodynamic phase diagram of amyloid-β (16–22) peptide

The aggregation of monomeric amyloid β protein (Aβ) peptide into oligomers and amyloid fibrils in the mammalian brain is associated with Alzheimer’s disease. Insight into the thermodynamic stability of the Aβ peptide in different polymeric states is fundamental to defining and predicting the aggrega...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Wang, Yiming, Bunce, Samuel J., Radford, Sheena E., Wilson, Andrew J., Auer, Stefan, Hall, Carol K.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369758/
https://ncbi.nlm.nih.gov/pubmed/30674664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819592116
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