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Effects of Hydrophobic Macromolecular Crowders on Amyloid β (16–22) Aggregation

In Alzheimer’s disease (AD), the amyloid β (Aβ) peptide aggregates in the brain to form progressively larger oligomers, fibrils, and plaques. The aggregation process is strongly influenced by the presence of other macromolecular species, called crowders, that can exert forces on the proteins. One ve...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Latshaw, David C., Hall, Carol K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571038/
https://ncbi.nlm.nih.gov/pubmed/26153709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.032
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