Effects of Hydroxylated Carbon Nanotubes on the Aggregation of Aβ(16–22) Peptides: A Combined Simulation and Experimental Study

The pathogenesis of Alzheimer’s disease (AD) is associated with the aggregation of amyloid-β (Aβ) peptides into toxic aggregates with β-sheet character. In a previous computational study, we showed that pristine single-walled carbon nanotubes (SWCNTs) can inhibit the formation of β-sheet-rich oligom...

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Bibliographische Detailangaben
Hauptverfasser: Xie, Luogang, Lin, Dongdong, Luo, Yin, Li, Huiyu, Yang, Xinju, Wei, Guanghong
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Proteins and Nucleic Acids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213673/
https://ncbi.nlm.nih.gov/pubmed/25418174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.034
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