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Antitumor Effects of Glychionide-A Flavonoid in Human Pancreatic Carcinoma Cells Are Mediated by Activation of Apoptotic and Autophagic Pathways, Cell Cycle Arrest, and Disruption of Mitochondrial Membrane Potential

BACKGROUND: Pancreatic cancer has high incidence and low survival rates around the globe, mainly due to late diagnosis and unavailability of efficient chemotherapeutic agents. In the present study, the anticancer potential of glychionide-A was examined against PANC-1 pancreatic cancer cells. MATERIA...

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Bibliografische gegevens
Gepubliceerd in:Med Sci Monit
Hoofdauteurs: Yu, Lei, Chen, Min, Zhang, Rui, Xu, Ting
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Scientific Literature, Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369652/
https://ncbi.nlm.nih.gov/pubmed/30712054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.913400
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