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Antitumor Effects of Glychionide-A Flavonoid in Human Pancreatic Carcinoma Cells Are Mediated by Activation of Apoptotic and Autophagic Pathways, Cell Cycle Arrest, and Disruption of Mitochondrial Membrane Potential

BACKGROUND: Pancreatic cancer has high incidence and low survival rates around the globe, mainly due to late diagnosis and unavailability of efficient chemotherapeutic agents. In the present study, the anticancer potential of glychionide-A was examined against PANC-1 pancreatic cancer cells. MATERIA...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Yu, Lei, Chen, Min, Zhang, Rui, Xu, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369652/
https://ncbi.nlm.nih.gov/pubmed/30712054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.913400
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