Anti-Proliferation and Pro-Apoptotic Effects of Diosmetin via Modulating Cell Cycle Arrest and Mitochondria-Mediated Intrinsic Apoptotic Pathway in MDA-MB-231 Cells

BACKGROUND: Breast cancer is one of the most malignant tumors worldwide. The natural flavonoid diosmetin has been reported to exhibit various pharmacological activities, including anti-cancer effects. This study aimed to investigate the anti-breast cancer effects of diosmetin on MDA-MB-231 cells and...

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Vydáno v:Med Sci Monit
Hlavní autoři: Wang, Chunjing, Li, Shujing, Ren, Huanhuan, Sheng, Yue, Wang, Tiantian, Li, Min, Zhou, Qiang, He, Hongxian, Liu, Changqing
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601365/
https://ncbi.nlm.nih.gov/pubmed/31228347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.914058
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