O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

Toxoplasma gondii is an intracellular parasite that causes disseminated infections that can produce neurological damage in fetuses and immunocompromised individuals. Microneme protein 2 (MIC2), a member of the thrombospondin-related anonymous protein (TRAP) family, is a secreted protein important fo...

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Vydáno v:J Biol Chem
Hlavní autoři: Bandini, Giulia, Leon, Deborah R., Hoppe, Carolin M., Zhang, Yue, Agop-Nersesian, Carolina, Shears, Melanie J., Mahal, Lara K., Routier, Françoise H., Costello, Catherine E., Samuelson, John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369279/
https://ncbi.nlm.nih.gov/pubmed/30538131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005179
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