The nucleocytosolic O-fucosyltransferase SPINDLY affects protein expression and virulence in Toxoplasma gondii

Once considered unusual, nucleocytoplasmic glycosylation is now recognized as a conserved feature of eukaryotes. While in animals, O-GlcNAc transferase (OGT) modifies thousands of intracellular proteins, the human pathogen Toxoplasma gondii transfers a different sugar, fucose, to proteins involved i...

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Publicat a:J Biol Chem
Autors principals: Bandini, Giulia, Agop-Nersesian, Carolina, van der Wel, Hanke, Mandalasi, Msano, Kim, Hyun W., West, Christopher M., Samuelson, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949088/
https://ncbi.nlm.nih.gov/pubmed/33158988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015883
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