Rapid control of protein level in the apicomplexan Toxoplasma gondii

Analysis of gene function in apicomplexan parasites is limited by the absence of reverse genetic tools that allow easy and rapid modulation of protein levels. The fusion of a ligand-controlled destabilization domain (ddFKBP) to a protein of interest enables rapid and reversible protein stabilization...

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Bibliografiske detaljer
Main Authors: Herm-Götz, Angelika, Agop-Nersesian, Carolina, Münter, Sylvia, Grimley, Joshua S, Wandless, Thomas J, Frischknecht, Friedrich, Meissner, Markus
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601725/
https://ncbi.nlm.nih.gov/pubmed/17994029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth1134
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