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Rapid control of protein level in the apicomplexan Toxoplasma gondii

Analysis of gene function in apicomplexan parasites is limited by the absence of reverse genetic tools that allow easy and rapid modulation of protein levels. The fusion of a ligand-controlled destabilization domain (ddFKBP) to a protein of interest enables rapid and reversible protein stabilization...

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Detalhes bibliográficos
Main Authors: Herm-Götz, Angelika, Agop-Nersesian, Carolina, Münter, Sylvia, Grimley, Joshua S, Wandless, Thomas J, Frischknecht, Friedrich, Meissner, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601725/
https://ncbi.nlm.nih.gov/pubmed/17994029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth1134
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