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C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence
C-Mannosylation is a common modification of thrombospondin type 1 repeats present in metazoans and recently identified also in apicomplexan parasites. This glycosylation is mediated by enzymes of the DPY19 family that transfer α-mannoses to tryptophan residues in the sequence WX(2)WX(2)C, which is p...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6983843/ https://ncbi.nlm.nih.gov/pubmed/31862733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010590 |
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