C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence

C-Mannosylation is a common modification of thrombospondin type 1 repeats present in metazoans and recently identified also in apicomplexan parasites. This glycosylation is mediated by enzymes of the DPY19 family that transfer α-mannoses to tryptophan residues in the sequence WX(2)WX(2)C, which is p...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Albuquerque-Wendt, Andreia, Jacot, Damien, Dos Santos Pacheco, Nicolas, Seegers, Carla, Zarnovican, Patricia, Buettner, Falk F. R., Bakker, Hans, Soldati-Favre, Dominique, Routier, Françoise H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983843/
https://ncbi.nlm.nih.gov/pubmed/31862733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010590
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