Vancomycin improves Plasmodium yoelii malaria parasite in vitro liver stage cultures by controlling Elizabethkingia anophelis, a bacterium in the microbiome of lab-reared Anopheles...

por Shears, Melanie J., Murphy, Sean C.
Publicado en Mol Biochem Parasitol (2020)

Important Extracellular Interactions between Plasmodium Sporozoites and Host Cells Required for Infection.

por Dundas, Kirsten, Shears, Melanie J., Sinnis, Photini, Wright, Gavin J.
Publicado en Trends Parasitol (2018)

Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models

por Shears, Melanie J., Seilie, Annette M., Kim Lee Sim, B., Hoffman, Stephen L., Murphy, Sean C.
Publicado en Malar J (2020)

Alpha-v–containing integrins are host receptors for the Plasmodium falciparum sporozoite surface protein, TRAP

por Dundas, Kirsten, Shears, Melanie J., Sun, Yi, Hopp, Christine S., Crosnier, Cecile, Metcalf, Tom, Girling, Gareth, Sinnis, Photini, Billker, Oliver, Wright, Gavin J.
Publicado en Proc Natl Acad Sci U S A (2018)

Proteomic Analysis of Plasmodium Merosomes: The Link between Liver and Blood Stages in Malaria

por Shears, Melanie J., Nirujogi, Raja Sekhar, Swearingen, Kristian E., Renuse, Santosh, Mishra, Satish, Reddy, Panga Jaipal, Moritz, Robert L., Pandey, Akhilesh, Sinnis, Photini
Publicado en J Proteome Res (2019)

O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

por Bandini, Giulia, Leon, Deborah R., Hoppe, Carolin M., Zhang, Yue, Agop-Nersesian, Carolina, Shears, Melanie J., Mahal, Lara K., Routier, Françoise H., Costello, Catherine E., Samuelson, John
Publicado en J Biol Chem (2019)

Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics

por Swearingen, Kristian E., Lindner, Scott E., Shi, Lirong, Shears, Melanie J., Harupa, Anke, Hopp, Christine S., Vaughan, Ashley M., Springer, Timothy A., Moritz, Robert L., Kappe, Stefan H. I., Sinnis, Photini
Publicado en PLoS Pathog (2016)

Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast

por Shears, Melanie J., MacRae, James I., Mollard, Vanessa, Goodman, Christopher D., Sturm, Angelika, Orchard, Lindsey M., Llinás, Manuel, McConville, Malcolm J., Botté, Cyrille Y., McFadden, Geoffrey I.
Publicado en Cell Microbiol (2016)

Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

por Lindner, Scott E., Swearingen, Kristian E., Shears, Melanie J., Walker, Michael P., Vrana, Erin N., Hart, Kevin J., Minns, Allen M., Sinnis, Photini, Moritz, Robert L., Kappe, Stefan H. I.
Publicado en Nat Commun (2019)

Lipid Profile Remodeling in Response to Nitrogen Deprivation in the Microalgae Chlorella sp. (Trebouxiophyceae) and Nannochloropsis sp. (Eustigmatophyceae)

por Martin, Gregory J. O., Hill, David R. A., Olmstead, Ian L. D., Bergamin, Amanda, Shears, Melanie J., Dias, Daniel A., Kentish, Sandra E., Scales, Peter J., Botté, Cyrille Y., Callahan, Damien L.
Publicado 2014

Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphat...

por Amiar, Souad, MacRae, James I., Callahan, Damien L., Dubois, David, van Dooren, Giel G., Shears, Melanie J., Cesbron-Delauw, Marie-France, Maréchal, Eric, McConville, Malcolm J., McFadden, Geoffrey I., Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Publicado en PLoS Pathog (2016)

Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites

por Botté, Cyrille Y., Yamaryo-Botté, Yoshiki, Rupasinghe, Thusitha W. T., Mullin, Kylie A., MacRae, James I., Spurck, Timothy P., Kalanon, Ming, Shears, Melanie J., Coppel, Ross L., Crellin, Paul K., Maréchal, Eric, McConville, Malcolm J., McFadden, Geoffrey I.
Publicado 2013

Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters

por McLean, Kyle Jarrod, Straimer, Judith, Hopp, Christine S., Vega-Rodriguez, Joel, Small-Saunders, Jennifer L., Kanatani, Sachie, Tripathi, Abhai, Mlambo, Godfree, Dumoulin, Peter C., Harris, Chantal T., Tong, Xinran, Shears, Melanie J., Ankarklev, Johan, Kafsack, Björn F. C., Fidock, David A., Sinnis, Photini
Publicado en Sci Rep (2019)