Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics

Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to developing a malaria vaccine is the use of proteins located on the sporozoite surface as antigens to elicit...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Pathog
Κύριοι συγγραφείς: Swearingen, Kristian E., Lindner, Scott E., Shi, Lirong, Shears, Melanie J., Harupa, Anke, Hopp, Christine S., Vaughan, Ashley M., Springer, Timothy A., Moritz, Robert L., Kappe, Stefan H. I., Sinnis, Photini
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851412/
https://ncbi.nlm.nih.gov/pubmed/27128092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005606
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