Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast

Malaria parasites can synthesize fatty acids via a type II fatty acid synthesis (FASII) pathway located in their apicoplast. The FASII pathway has been pursued as an anti‐malarial drug target, but surprisingly little is known about its role in lipid metabolism. Here we characterize the apicoplast gl...

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Bibliographic Details
Published in:Cell Microbiol
Main Authors: Shears, Melanie J., MacRae, James I., Mollard, Vanessa, Goodman, Christopher D., Sturm, Angelika, Orchard, Lindsey M., Llinás, Manuel, McConville, Malcolm J., Botté, Cyrille Y., McFadden, Geoffrey I.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213128/
https://ncbi.nlm.nih.gov/pubmed/27324409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12633
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