Age-related Disturbances in DNA (hydroxy)methylation in APP/PS1 Mice

Brain aging has been associated with aberrant DNA methylation patterns, and changes in the levels of DNA methylation and associated markers have been observed in the brains of Alzheimer’s disease (AD) patients. DNA hydroxymethylation, however, has been sparsely investigated in aging and AD. We have...

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Bibliographic Details
Published in:Transl Neurosci
Main Authors: Chouliaras, Leonidas, Lardenoije, Roy, Kenis, Gunter, Mastroeni, Diego, Hof, Patrick R., van Os, Jim, Steinbusch, Harry W.M., van Leeuwen, Fred W., Rutten, Bart P.F., van den Hove, Daniel L.A.
Format: Artigo
Language:Inglês
Published: De Gruyter 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368665/
https://ncbi.nlm.nih.gov/pubmed/30746282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/tnsci-2018-0028
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