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Age-related Disturbances in DNA (hydroxy)methylation in APP/PS1 Mice

Brain aging has been associated with aberrant DNA methylation patterns, and changes in the levels of DNA methylation and associated markers have been observed in the brains of Alzheimer’s disease (AD) patients. DNA hydroxymethylation, however, has been sparsely investigated in aging and AD. We have...

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Detalhes bibliográficos
Publicado no:Transl Neurosci
Main Authors: Chouliaras, Leonidas, Lardenoije, Roy, Kenis, Gunter, Mastroeni, Diego, Hof, Patrick R., van Os, Jim, Steinbusch, Harry W.M., van Leeuwen, Fred W., Rutten, Bart P.F., van den Hove, Daniel L.A.
Formato: Artigo
Idioma:Inglês
Publicado em: De Gruyter 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368665/
https://ncbi.nlm.nih.gov/pubmed/30746282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/tnsci-2018-0028
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