Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction

Aberrant DNA methylation patterns have been linked to molecular and cellular alterations in the aging brain. Caloric restriction (CR) and upregulation of antioxidants have been proposed as interventions to prevent or delay age-related brain pathology. Previously, we have shown in large cohorts of ag...

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Main Authors: Chouliaras, Leonidas, van den Hove, Daniel L.A., Kenis, Gunter, Keitel, Stella, Hof, Patrick R., van Os, Jim, Steinbusch, Harry W.M., Schmitz, Christoph, Rutten, Bart P.F.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355211/
https://ncbi.nlm.nih.gov/pubmed/21764481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.06.003
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