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Transcriptional burst initiation and polymerase pause release are key control points of transcriptional regulation

Transcriptional regulation occurs via changes to rates of different biochemical steps of transcription, but it remains unclear which rates are subject to change upon biological perturbation. Biochemical studies have suggested that stimuli predominantly affect the rates of RNA polymerase II (Pol II)...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Bartman, Caroline R., Hamagami, Nicole, Keller, Cheryl A., Giardine, Belinda, Hardison, Ross C., Blobel, Gerd A., Raj, Arjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368450/
https://ncbi.nlm.nih.gov/pubmed/30554946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.004
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