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Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility
Single-nucleotide variants that underlie phenotypic variation can affect chromatin occupancy of transcription factors (TFs). To delineate determinants of in vivo TF binding and chromatin accessibility, we introduce an approach that compares ChIP-seq and DNase-seq data sets from genetically divergent...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823854/ https://ncbi.nlm.nih.gov/pubmed/29472540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03082-6 |
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