A carregar...
Two‐stage design for phase I–II cancer clinical trials using continuous dose combinations of cytotoxic agents
We present a two-stage phase I/II design of a combination of two drugs in cancer clinical trials. The goal is to estimate safe dose combination regions with a desired level of efficacy. In stage I, conditional escalation with overdose control is used to allocate dose combinations to successive cohor...
Na minha lista:
| Publicado no: | J R Stat Soc Ser C Appl Stat |
|---|---|
| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368405/ https://ncbi.nlm.nih.gov/pubmed/30745708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12294 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|