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A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

It has been more than a dozen years since FGF21 burst on the metabolism field in a paper showing that its pharmacologic administration caused weight loss and improved insulin sensitivity and lipoprotein profiles in obese rodents. Since then, FGF21 analogs have advanced all the way to clinical trials...

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Библиографические подробности
Опубликовано в: :Cell Metab
Главные авторы: Kliewer, Steven A., Mangelsdorf, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368396/
https://ncbi.nlm.nih.gov/pubmed/30726758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.01.004
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