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A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

It has been more than a dozen years since FGF21 burst on the metabolism field in a paper showing that its pharmacologic administration caused weight loss and improved insulin sensitivity and lipoprotein profiles in obese rodents. Since then, FGF21 analogs have advanced all the way to clinical trials...

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Dettagli Bibliografici
Pubblicato in:Cell Metab
Autori principali: Kliewer, Steven A., Mangelsdorf, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368396/
https://ncbi.nlm.nih.gov/pubmed/30726758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.01.004
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