Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort

AIM: Previous studies suggest telomere shortening represses PGC1A and PGC1B expression leading to mitochondrial dysfunction. Methylation of CpG sites within these genes may interact with these factors to affect cancer risk. MATERIALS & METHODS: Among 385 men, we identified 84 incidents of cancer...

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Publicado en:Epigenomics
Main Authors: Kresovich, Jacob K, Joyce, Brian T, Gao, Tao, Zheng, Yinan, Zhang, Zhou, Achenbach, Christopher J, Murphy, Robert L, Just, Allan C, Shen, Jincheng, Yang, Hushan, Vokonas, Pantel, Schwartz, Joel, Baccarelli, Andrea A, Hou, Lifang
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367713/
https://ncbi.nlm.nih.gov/pubmed/29888964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2017-0141
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