Prospective changes in global DNA methylation and cancer incidence and mortality

BACKGROUND: Methylation of repetitive elements Alu and LINE-1 in humans is considered a surrogate for global DNA methylation. Previous studies of blood-measured Alu/LINE-1 and cancer risk are inconsistent. METHODS: We studied 1259 prospective methylation measurements from blood drawn 1–4 times from...

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Dades bibliogràfiques
Publicat a:Br J Cancer
Autors principals: Joyce, Brian T, Gao, Tao, Zheng, Yinan, Liu, Lei, Zhang, Wei, Dai, Qi, Shrubsole, Martha J, Hibler, Elizabeth A, Cristofanilli, Massimo, Zhang, Hu, Yang, Hushan, Vokonas, Pantel, Cantone, Laura, Schwartz, Joel, Baccarelli, Andrea, Hou, Lifang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985350/
https://ncbi.nlm.nih.gov/pubmed/27351216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.205
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