Prospective changes in global DNA methylation and cancer incidence and mortality

BACKGROUND: Methylation of repetitive elements Alu and LINE-1 in humans is considered a surrogate for global DNA methylation. Previous studies of blood-measured Alu/LINE-1 and cancer risk are inconsistent. METHODS: We studied 1259 prospective methylation measurements from blood drawn 1–4 times from...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Joyce, Brian T, Gao, Tao, Zheng, Yinan, Liu, Lei, Zhang, Wei, Dai, Qi, Shrubsole, Martha J, Hibler, Elizabeth A, Cristofanilli, Massimo, Zhang, Hu, Yang, Hushan, Vokonas, Pantel, Cantone, Laura, Schwartz, Joel, Baccarelli, Andrea, Hou, Lifang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985350/
https://ncbi.nlm.nih.gov/pubmed/27351216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.205
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