Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort

AIM: Previous studies suggest telomere shortening represses PGC1A and PGC1B expression leading to mitochondrial dysfunction. Methylation of CpG sites within these genes may interact with these factors to affect cancer risk. MATERIALS & METHODS: Among 385 men, we identified 84 incidents of cancer...

詳細記述

保存先:
書誌詳細
出版年:Epigenomics
主要な著者: Kresovich, Jacob K, Joyce, Brian T, Gao, Tao, Zheng, Yinan, Zhang, Zhou, Achenbach, Christopher J, Murphy, Robert L, Just, Allan C, Shen, Jincheng, Yang, Hushan, Vokonas, Pantel, Schwartz, Joel, Baccarelli, Andrea A, Hou, Lifang
フォーマット: Artigo
言語:Inglês
出版事項: Future Medicine Ltd 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367713/
https://ncbi.nlm.nih.gov/pubmed/29888964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2017-0141
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