Prospective changes in global DNA methylation and cancer incidence and mortality

BACKGROUND: Methylation of repetitive elements Alu and LINE-1 in humans is considered a surrogate for global DNA methylation. Previous studies of blood-measured Alu/LINE-1 and cancer risk are inconsistent. METHODS: We studied 1259 prospective methylation measurements from blood drawn 1–4 times from...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Cancer
Prif Awduron: Joyce, Brian T, Gao, Tao, Zheng, Yinan, Liu, Lei, Zhang, Wei, Dai, Qi, Shrubsole, Martha J, Hibler, Elizabeth A, Cristofanilli, Massimo, Zhang, Hu, Yang, Hushan, Vokonas, Pantel, Cantone, Laura, Schwartz, Joel, Baccarelli, Andrea, Hou, Lifang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Molecular Diagnostics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985350/
https://ncbi.nlm.nih.gov/pubmed/27351216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.205
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