Prospective changes in global DNA methylation and cancer incidence and mortality

BACKGROUND: Methylation of repetitive elements Alu and LINE-1 in humans is considered a surrogate for global DNA methylation. Previous studies of blood-measured Alu/LINE-1 and cancer risk are inconsistent. METHODS: We studied 1259 prospective methylation measurements from blood drawn 1–4 times from...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Joyce, Brian T, Gao, Tao, Zheng, Yinan, Liu, Lei, Zhang, Wei, Dai, Qi, Shrubsole, Martha J, Hibler, Elizabeth A, Cristofanilli, Massimo, Zhang, Hu, Yang, Hushan, Vokonas, Pantel, Cantone, Laura, Schwartz, Joel, Baccarelli, Andrea, Hou, Lifang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Molecular Diagnostics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985350/
https://ncbi.nlm.nih.gov/pubmed/27351216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.205
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