Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas

There is a pressing need for more effective therapies to treat patients with T-cell lymphomas (TCLs), including first-line approaches that increase the response rate to cyclophosphamide, adriamycin, vincristine, and prednisone (CHOP) chemotherapy. We characterized the mitochondrial apoptosis pathway...

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Bibliographic Details
Published in:Blood
Main Authors: Koch, Raphael, Christie, Amanda L., Crombie, Jennifer L., Palmer, Adam C., Plana, Deborah, Shigemori, Kay, Morrow, Sara N., Van Scoyk, Alexandria, Wu, Wenchao, Brem, Elizabeth A., Secrist, J. Paul, Drew, Lisa, Schuller, Alwin G., Cidado, Justin, Letai, Anthony, Weinstock, David M.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2019
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367646/
https://ncbi.nlm.nih.gov/pubmed/30498064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-07-865527
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