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Uncoupling Sae2 Functions in Downregulation of Tel1 and Rad53 Signaling Activities
The Mre11-Rad50-Xrs2 (MRX) complex acts together with the Sae2 protein to initiate resection of DNA double-strand breaks (DSBs) and to regulate a checkpoint response that couples cell cycle progression with DSB repair. Sae2 supports resistance to DNA damage and downregulates the signaling activities...
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| Опубликовано в: : | Genetics |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366920/ https://ncbi.nlm.nih.gov/pubmed/30538107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301830 |
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