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Hematopoietic chimerism and donor-specific skin allograft tolerance after non-genotoxic CD117 antibody-drug-conjugate conditioning in MHC-mismatched allotransplantation

Hematopoietic chimerism after allogeneic bone marrow transplantation may establish a state of donor antigen-specific tolerance. However, current allotransplantation protocols involve genotoxic conditioning which has harmful side-effects and predisposes to infection and cancer. Here we describe a non...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Li, Zhanzhuo, Czechowicz, Agnieszka, Scheck, Amelia, Rossi, Derrick J., Murphy, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365540/
https://ncbi.nlm.nih.gov/pubmed/30728353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08202-w
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