LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency

The molecular basis for the formation of functional, higher-ordered macro-molecular domains is not completely known. The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) genome forms a super-molecular domain structure during latent infection that is strictly dependent on the DNA binding of the viral n...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: De Leo, Alessandra, Deng, Zhong, Vladimirova, Olga, Chen, Horng-Shen, Dheekollu, Jayaraju, Calderon, Abram, Myers, Kenneth A., Hayden, James, Keeney, Frederick, Kaufer, Benedikt B., Yuan, Yan, Robertson, Erle, Lieberman, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364946/
https://ncbi.nlm.nih.gov/pubmed/30682185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007489
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