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The Universally Unrecognized Assumption in Predicting Drug Clearance and Organ Extraction Ratio

For almost a half-century clearance concepts have been utilized in pharmacokinetics to understand the relationship between the dose administered and the time course of systemic concentrations to predict efficacy and safety, as well as how dosing should be modified in disease states. Various models o...

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Detaylı Bibliyografya
Yayımlandı:Clin Pharmacol Ther
Asıl Yazarlar: Benet, LZ, Liu, S, Wolfe, AR
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364827/
https://ncbi.nlm.nih.gov/pubmed/28762489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.802
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