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The Universally Unrecognized Assumption in Predicting Drug Clearance and Organ Extraction Ratio
For almost a half-century clearance concepts have been utilized in pharmacokinetics to understand the relationship between the dose administered and the time course of systemic concentrations to predict efficacy and safety, as well as how dosing should be modified in disease states. Various models o...
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| Publicado no: | Clin Pharmacol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364827/ https://ncbi.nlm.nih.gov/pubmed/28762489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.802 |
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