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The A-type domain in Escherichia coli NfuA is required for regenerating the auxiliary [4Fe–4S] cluster in Escherichia coli lipoyl synthase

The lipoyl cofactor plays an integral role in several essential biological processes. The last step in its de novo biosynthetic pathway, the attachment of two sulfur atoms at C6 and C8 of an n-octanoyllysyl chain, is catalyzed by lipoyl synthase (LipA), a member of the radical SAM superfamily. In ad...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: McCarthy, Erin L., Rankin, Ananda N., Dill, Zerick R., Booker, Squire J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364782/
https://ncbi.nlm.nih.gov/pubmed/30538130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006171
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