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Regulation of the Activity of Escherichia coli Quinolinate Synthase by Reversible Disulfide-Bond Formation†
Quinolinate synthase (NadA) catalyzes a unique condensation reaction between dihydroxyacetone phosphate and iminoaspartate, yielding inorganic phosphate, 2 mol of water, and quinolinic acid, a central intermediate in the biosynthesis of nicotinamide adenine dinucleotide and its derivatives. The enzy...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319134/ https://ncbi.nlm.nih.gov/pubmed/18651751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801135y |
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