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Activation of the lifespan regulator p66(Shc) through reversible disulfide bond formation

Cell fate and organismal lifespan are controlled by a complex signaling network whose dysfunction can cause a variety of aging-related diseases. An important protection against these failures is cellular apoptosis, which can be induced by p66(Shc) in response to cellular stress. The precise mechanis...

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Bibliografski detalji
Glavni autori: Gertz, Melanie, Fischer, Frank, Wolters, Dirk, Steegborn, Clemens
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311372/
https://ncbi.nlm.nih.gov/pubmed/18413607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800691105
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