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Activation of the lifespan regulator p66(Shc) through reversible disulfide bond formation
Cell fate and organismal lifespan are controlled by a complex signaling network whose dysfunction can cause a variety of aging-related diseases. An important protection against these failures is cellular apoptosis, which can be induced by p66(Shc) in response to cellular stress. The precise mechanis...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311372/ https://ncbi.nlm.nih.gov/pubmed/18413607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800691105 |
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