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Aberrant Expression of p14(ARF) in Human Cancers: A New Biomarker?
The ARF and INK4a genes are located on the CDKN2a locus, both showing tumor suppressive activity. ARF has been shown to monitor potentially harmful oncogenic signalings, making early stage cancer cells undergo senescence or programmed cell death to prevent cancer. Conversely, INK4a detects both agin...
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| Veröffentlicht in: | Tumor Microenviron |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364748/ https://ncbi.nlm.nih.gov/pubmed/30740529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/tme.tme_24_17 |
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