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Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancer

Alternative splicing of mRNA precursors is a ubiquitous mechanism for generating numerous transcripts with different activities from one genomic locus in mammalian cells. The gene products from a single locus can thus have similar, dominant-negative, or even opposing functions. Aberrant alternative...

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Bibliografiske detaljer
Udgivet i:Int J Cancer
Main Authors: Inoue, Kazushi, Fry, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047959/
https://ncbi.nlm.nih.gov/pubmed/26802432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30003
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