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Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction

Sirt1 is an NAD-dependent, class III deacetylase that functions as a cellular energy sensor. In addition to its well-characterized effects in peripheral tissues, emerging evidence suggests that neuronal Sirt1 activity plays a role in the central regulation of energy balance and glucose metabolism. I...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Rickert, Emily, Fernandez, Marina O, Choi, Irene, Gorman, Michael, Olefsky, Jerrold M, Webster, Nicholas J G
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364627/
https://ncbi.nlm.nih.gov/pubmed/30746504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2018-00318
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