Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction

Skeletal muscle insulin resistance is a key component of the etiology of type 2 diabetes. Caloric restriction (CR) enhances the sensitivity of skeletal muscle to insulin. However, the molecular signals within skeletal muscle linking CR to improved insulin action remain largely unknown. Recently, the...

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Detalhes bibliográficos
Main Authors: Schenk, Simon, McCurdy, Carrie E., Philp, Andrew, Chen, Mark Z., Holliday, Michael J., Bandyopadhyay, Gautum K., Osborn, Olivia, Baar, Keith, Olefsky, Jerrold M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204844/
https://ncbi.nlm.nih.gov/pubmed/21985785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58554
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