Calorie Restriction-Induced Increase in Skeletal Muscle Insulin Sensitivity Is Not Prevented by Overexpression of the p55α Subunit of Phosphoinositide 3-Kinase

Introduction: The Phosphoinositide 3-kinase (PI3K) signaling pathway plays an important role in skeletal muscle insulin-stimulated glucose uptake. While whole-body and tissue specific knockout (KO) of individual or combinations of the regulatory subunits of PI3K (p85α, p55α, and p50α or p85β); incre...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Martins, Vitor F., Tahvilian, Shahriar, Kang, Ji H., Svensson, Kristoffer, Hetrick, Byron, Chick, Wallace S., Schenk, Simon, McCurdy, Carrie E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030672/
https://ncbi.nlm.nih.gov/pubmed/29997524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00789
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