Plasma Agouti-Related Protein and Cortisol Levels in Cushing Disease: Evidence for the Regulation of Agouti-Related Protein by Glucocorticoids in Humans

CONTEXT: Glucocorticoids regulate energy balance, in part by stimulating the orexigenic neuropeptide agouti-related protein (AgRP). AgRP neurons express glucocorticoid receptors, and glucocorticoids have been shown to stimulate AgRP gene expression in rodents. OBJECTIVE: We sought to determine wheth...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Page-Wilson, Gabrielle, Peters, Jane B, Panigrahi, Sunil K, Jacobs, Thomas P, Korner, Judith, Otten, Marc, Bruce, Jeffrey N, Wardlaw, Sharon L
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364508/
https://ncbi.nlm.nih.gov/pubmed/30597030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-01909
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