Cerebrospinal Fluid Levels of Leptin, Proopiomelanocortin, and Agouti-Related Protein in Human Pregnancy: Evidence for Leptin Resistance

CONTEXT: Leptin suppresses appetite by modulating the expression of hypothalamic neuropeptides including proopiomelanocortin (POMC) and agouti-related peptide (AgRP). Yet during pregnancy, caloric consumption increases despite elevated plasma leptin levels. DESIGN AND PARTICIPANTS: To investigate th...

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Detalhes bibliográficos
Main Authors: Page-Wilson, Gabrielle, Reitman-Ivashkov, Elena, Meece, Kana, White, Anne, Rosenbaum, Michael, Smiley, Richard M., Wardlaw, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Endocrine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537103/
https://ncbi.nlm.nih.gov/pubmed/23118421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-2309
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