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Proopiomelanocortin, agouti-related protein, and leptin in human cerebrospinal fluid: correlations with body weight and adiposity

Leptin and its neuronal targets, which produce proopiomelanocortin (POMC) and agouti-related protein (AgRP), regulate energy balance. This study characterized leptin, POMC, and AgRP in the cerebrospinal fluid (CSF) of 47 healthy human subjects, 23 lean and 24 overweight/obese (OW/OB), as related to...

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Détails bibliographiques
Publié dans:Am J Physiol Endocrinol Metab
Auteurs principaux: Page-Wilson, Gabrielle, Meece, Kana, White, Anne, Rosenbaum, Michael, Leibel, Rudolph L., Smiley, Richard, Wardlaw, Sharon L.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556883/
https://ncbi.nlm.nih.gov/pubmed/26152765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00206.2015
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