Plasma Agouti-Related Protein Levels in Acromegaly and Effects of Surgical or Pegvisomant Therapy

CONTEXT: GH activates agouti-related protein (AgRP) neurons, leading to orexigenic responses in mice. The relationship between serum GH and plasma AgRP, which has been shown to reflect hypothalamic AgRP, has not been evaluated in humans. OBJECTIVE: To test the hypothesis that central stimulatory act...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Freda, Pamela U, Reyes-Vidal, Carlos, Jin, Zhezhen, Pugh, Mya, Panigrahi, Sunil K, Bruce, Jeffrey N, Wardlaw, Sharon L
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777636/
https://ncbi.nlm.nih.gov/pubmed/31361303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2019-01079
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